Senior Scientist, Phenotypic Imaging position– MoA-GALAXY

Protoplast cells

moa is recruiting for a Senior Scientist, Phenotypic Imaging position– MoA-GALAXY

Company

MoA’s mission is to find a new generation of safe and effective herbicides to help farmers produce high quality food. To achieve this goal, we have developed 3 unique and complementary platforms: MoA-GALAXY, MoA-TARGET and MoA-SELECT. The post-holder will be part of the MoA-GALAXY team.

MoA-GALAXY is a unique proprietary, High Throughput Screening (HTS) platform for finding herbicides with new modes of action (MOA). We use state-of-the-art screening and imaging technologies to generate a wide range of herbicidal activity data.  

We have an exciting opportunity for a talented and highly motivated Senior Scientist to join the GALAXY team at MoA. The successful applicant will integrate into a dynamic group to support and advance our early herbicide discovery pipeline. The candidate will work on exciting new projects to accelerate the characterization of new MOA herbicides. Using qualitative and quantitative imaging, the selected candidate will make significant contributions to the profiling of hit compounds by designing, validating, and executing cellular phenotypic assays.

This position will provide ample opportunities for skillset development and career building.

Candidates with a strong background in cell biology, advanced imaging confocal and wide-field microscopy, high-content assay development and miniaturization are strongly encouraged to apply.

The Role

Position type: Permanent full-time - 37.5 hours per week

Salary: Competitive

Location: The Bellhouse Building, The Magdalen Centre, The Oxford Science Park, Robert Robinson Avenue, Oxford, OX4 4GA

Required qualifications and experience:

The post-holder will hold:

  • PhD in life sciences, biology or another related scientific area with more than 5 years of relevant postdoctoral experience.  
  • Proven track record of successful delivery of scientific projects  as evidenced by means of publications demonstrating the use of advanced imaging platforms including confocal and wide-field microscopy.
  • Strong expertise in cell biology.
  • Strong expertise with setup and optimization of miniaturised in vivo assays.
  • Broad knowledge of high-content imaging readers and image analysis is highly desirable.
  • Experience working with an emerging plant model system is highly desirable.
  • Computer skills to handle large datasets and image analyses using specialized software applications.
  • Proven experience in phenotypic screening, either through genetic or drug discovery approaches.
  • Proven ability to analyse and interpret complex phenotypic data.

Role and responsibilities

Responsibilities include:

  1. Develop and execute phenotypic screens to profile active compounds in new MOA herbicide discovery.
  2. Develop reporter assays to interrogate complex biology.
  3. Execute proof-of-concept studies and pilot screens to reveal technical challenges and identify suitable solutions.
  4. Validate protocols for new assays, enabling their integration into standard workflows.
  5. Analyse, interpret and communicate experimental results in collaboration with biology and chemistry teams.
  6. Contribute to the execution of new mythologies applied to image-based assays.  
  7. Participate in trial and acquisition of new imaging instruments, including preparation of scientific proposals.
  8. Participate in shaping the infrastructure of the imaging platforms to accompany company growth and diversification.
  9. Identify and implement innovative solutions applicable to high-content imaging paradigms.
  10. Present findings to a broad range of audience, publish data reports and generate SOPs.
  11. Provide mentorship and guidance to junior members of staff and peers
  12. Generate new research project proposals and contribute to wider project planning.
  13. Contribute to a culture that values impactful scientific discoveries and encourages personal development.  

Knowledge, Skills and Abilities:

The ideal candidate will possess:

  1. Proven ability to work collaboratively with diverse and multidisciplinary teams. Strong communication skills both in writing and at meetings with relevant stakeholders.  
  2. Strong organisational skills that enable autonomous time management and prioritization of multiple project and  diverse daily activities.
  3. Strong attention to detail and accuracy.
  4. Pro-active and positive problem solving mindset.
  5. Be enthused by the science and MoA ’s vision.
  6. Be adaptable. The company is in a rapid growth trajectory and requires individuals who can evolve with the needs of the business.
  7. Be a good colleague: the platforms are very collaborative and require a team player.  
  8. Have a good work ethic, display a high level of professionalism and be reliable.  
  9. Adhere to company’s policies and standard business etiquette.
  10. Industrial experience is an advantage but not essential.  

Eligibility

MoA is strongly committed to the safety of their employees and in the current COVID-19 climate, have taken measures that require the post-holder to:

  • Live in the Oxford area and have means to commute. Candidates who do not currently live in the Oxford area should be able to provide evidence that they can relocate in a timely and safely manner.
  • Work flexible hours and be opened to work weekends, early mornings (~7:00-9:00) or evenings (~17:00-22:00), in order to maintain social distancing. As the Government relaxes safe social distancing rules and allows a return to normal working practices we will also revert to our normal working arrangements (Mon-Fri, 9am -5pm).
  • MoA is an equal opportunity employer and encourages applications from all candidates irrespective of gender, race, disability, sexual orientation, religion/belief, or age.
  • Must be legally able to live and work in the UK.

Please send a CV and cover letter to hr@moa-technology.com

MoA190819.pdf